Synthesis of W-based photothermal nanoagents for the therapy of tumor.pdf

1、The high temperatures achieved in PTA were sufficient in damage of cancer cells as was witnessed in the H&E staining examination. Thus the (NH4)xWO3-PEG has shown potential as theranostic probes for both diagnostic and t

2、herapy.
　　We also prepared WS2 through high-temperature treatment in a liquid-phase synthesis strategy in high-boiling solvent. Characterization through TEM showed that the resultant WS2 nanomaterials to be nanowires

3、of 2nm thickness and 100nm length. Furthermore, the SAED image revealed several diffraction rings, indicating the polycrystalline nature of WS2 nanowires. Further evidence of WS2 synthesis was provided by the EDS image s

4、howing only the presence of W and S. Surface functionalization determined by the FT-IR spectra showed capping on oleylamine ligands on the surface of the nanowires. Evaluation of their photoabsorption by the UV-vis-NIR r

5、evealed broad absorption in the NIR region (700-1100nm). Their photothermal conversion under 808nm wavelength laser was excellent at only very low concentrations. These results describe a potential photothermal nanoagent