集成多通道生物傳感器生物敏感膜制備與應用軟件開發(fā).pdf

1、南開大學碩士學位論文集成多通道生物傳感器生物敏感膜制備與應用軟件開發(fā)姓名：王延濤申請學位級別：碩士專業(yè)：電子科學與技術；電路與系統(tǒng)指導教師：劉國華201105AbstractAbstractSPR(SurfacePlasmonResonance)biosensordetectandanalysistheinteractionsbetweenbiologicalmoleculesbyobservingchangesofresonancea

2、ngleinthesurfaceofbio—chipByusingthemethodofopticsdetectionSPRbiosensorhastheadvantagesofnolabelingofthemoleculesandanalyzinginRealtimewithlfilghsensitivityInthisthesis，wefocusontheresearchofbiochipandthedevelopmentofthe

3、biosensorsystemapplicationsoftwareTheimmobilizationofprobemoleculesisthemostimportantpartofthefabricationofbio—chipWeimmobilizetheGoatantihumanIgGwiththetechnologyofSAMs(selfassembledmonolayer)Onthisbase，byusingthemixedt

4、hiolsolutionreplacingthepuresolutionthedensityofantibodyimmobilized011thesurfaceofselfassembledmonolayerisreducedandthebindingsitesofantibodyisexposedtotheantigenThereforetherateofantibodyantigenbindinghasbeenimprovedrem

5、arkableThespatialdirectionofantibodyimmobilizedhassignificantinfluenceintherateofantibodyantigenbindingWesummarizedtwomethodsofcontrollingtheimmobilizationofantibodyanditsspatialdirection，thenanalyzedtheresultofexperimen

6、talApplicationsoftwareisalsoanimportantpartofbiosensorsystemWeillustratedtheoverallstructureofapplicationsoftwareintwoways，thecompositionoftheclassesandthefunctionalcomponentsThenweillustratedthedevelopmentofmainfunction

7、sindetailThisapplicationsoRwareisbasedonMFCview／documentfTamework，withthefunctionofcommunicationwiththecircuitdispl咖ngwavesdynamicallyBybeingcarefullytestedandoptimized，thissoftwarehasexcellentscalabilityandstabilityKeyw