白鮮皮提取物抗過(guò)敏作用的實(shí)驗(yàn)研究以及在濕疹中的運(yùn)用.pdf

1、成都中醫(yī)藥大學(xué)碩士學(xué)位論文白鮮皮提取物抗過(guò)敏作用的實(shí)驗(yàn)研究以及在濕疹中的運(yùn)用姓名：唐忠芬申請(qǐng)學(xué)位級(jí)別：碩士專業(yè)：中醫(yī)外科學(xué)指導(dǎo)教師：張毅20060401成都中醫(yī)藥大學(xué)碗士學(xué)位論文AbstractObjective：Todetecttheanti—hypersensitivityeffectofCortexDictamni’extractionbasedonani眥lmodelTQresearchthemechanismofanti—hy

2、persensitivityprelimarilyfortreatingeczemainclinicMethods：firstly，todetectthediametersofblueplaqueontype1allergicSDratsmodelsSecondly，todetectthewholedoseofCTXusedfortheitchingguineapigmodelcausedbyhistamineThirdly，tores

3、erchthethetypeIVhypersensitivityinducedbyDNCB，attheSDJnetimestudytheswollenearsofsmallratsResult：1A11dosesofCortexDictamni’extractioncaninhibitthebuleplaqueofSDratsbacksignifacantly(pO01)。whichmeansCortexDictamni’extract

4、ioncaninhibitthetypeIhypersensitivityCortexDictamni’extraction2thatlargeandmiddledosegroupofCortexDictamni’extractioncanincreaseitchingthreshold(pO05)，whichmeansCortexDictamni’extractioncanstopitchingeffectively3thatlarg

5、edosegroupofCortexDictamni’extractioncaninhibitthedelayedskinhypersensitivitycausedbyDNCB，anddecreasethesw011enearsofsmalIrats(pO05)Conclusion：CortexDictamni’extractioncaninhibitthetypeIandIVhypersensitivityeffectivelyKe