27051.初級視皮層對刺激特征的時間響應(yīng)性質(zhì)及功能組織

1、分類號UDC密級編號中國科學(xué)院研究生院博士學(xué)位論文李驍健指導(dǎo)教師垂夔受究雖圭重疊堂院生塑塑毽受塞逝申請學(xué)位級男|l熊圭學(xué)科專業(yè)名稱生塑塑壅堂論文提交日期至Ql魚生墨旦論文答辯日期至Q!魚生魚復(fù)培養(yǎng)單位主圜抖堂瞳生塑物理嬰塞逝學(xué)位授予單位生國科堂院研究生陵二零一零年六月Abstract日leconsecutivechangeoftransientgratingstimulicouldinducethepsychologicalphenom

2、enonofcrossorientationmasking，butthestimulipresentedforalongerperiodorwithaninterstimulusintervalcouldbeclearlydistinguished。nephenomemonhasbeenthoughttolinktothephysiologicaleffectofcrossorientationsuppressionobservedin

3、singleneuronsintheprimaryvisualcortex(voIsthereanyotherneuralprocessresponsibleforthephenomenonofcrossorientationmaskingInordertounderstandtheunderlyingmechanisms，westudiedthetemporalpropertiesofresponsesofneuronsincatpr

4、imaryvisualcortextothestimulistaticallyandbrieflypresentedfor5to50mseitherwithorwithoutaninterstimulusintervalof80mstomimicthetwosituationsaboveToanalyzethetimecoursesoftheneuronalresponsestothetwomodesofstimulations，wed

5、evelopedanewdeconvolutionalgorithmmodifiedfromthereversecorrelationmethod硼1calgorithmcatchesthepropertiesofdynamicalresponsesoftheneuronstothe仃ansientchangeofvisualstimuliWeshowthat：(11responsestoorientationintheinterrup

6、tedmodewereearlierthanintheconsecutivemode，suggestingthattherapidlyconsecutivechangeofvisualstimulicandelaytheprocessingoforientationinformation；f2)theprofileofthemainpeakoftheresponsecurvegraduallyincreasedandsaturatedw

7、iththeincreaseinstimulusperioduptoabout40ms，revealingtheconstrainofneuralcircuittothemaximalamountofstimulusinformationthataneuroncallcarry：(3)themeanresponseperiodto5and10msstimuliintheinterruptedmodewas36msthatmightbet

8、hetimeneededforVlneuronstoencodetheessentialinformalionaboutorientations；(4)theresponseperiodundertheconsecutivemodeWaslargerthanthestimulationperiodwhichpossiblymaybeoneofthemechanismsunderlyingthephenomenonofcross—orie

9、ntationmaskingMoreoverwedevelopedamathematicalmodelbasedontheconvolutionalgorithmtodescribetheneuralprocessesgeneratingthesaturatedresponsepropertyweshowedabove強emodelingresponsesoftheprimaryvisualcorticalneuronstothetra

10、nsientstimuliwereconsistentwithafewresponsepropertiesrevealedbysomeotherstudiesAdditionallyusingtheintrinsicopticalimagingtechnique，weinvestigatedwhethercatprimaryvisualcortexcontainstllefunctionaldomainsencodingtherever

11、saltemporalfrequencythathasbeenrevealedbv△艇UinhumanprimaryvisualcortexOurdatashowthatthedomainsrevealedbyopticalimagingincatmightbetheconicalactivitypatternthatreflectedthetopographicalrepresentationofthestimuluspatternu

12、sed，butnottherepresentationofthetemporalfrequencysupportingtheconclusionthatVlcellsselectiveforaparticulartemporalfrequencyarenotarrangedintoacorticalcolumnasreportedbytheotherrecentstudyKeywords：cat：primaryvisualcortex：