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1、復(fù)旦大學(xué)新視野系列研究生課程:科研論文的構(gòu)思、撰寫和發(fā)表,科研論文撰寫和送審過程中導(dǎo)師和學(xué)生的互動(dòng),,楊雄里 院士,下一次今晚6時(shí):蒲慕明教授 “怎樣學(xué)習(xí)做一個(gè)好的科學(xué)家”,楊雄里院士神經(jīng)生物學(xué)家,1963年上海科技大學(xué)生物系畢業(yè),1963-1999年在中國科學(xué)院上海生理研究所工作,歷任研究實(shí)習(xí)員、助理研究員、副研究員、研究員、所長。1980-1982年在日本進(jìn)修并獲學(xué)術(shù)博士學(xué)位。1985-1987年先后在美國哈佛大學(xué)、貝勒醫(yī)學(xué)院

2、從事合作研究。2000年創(chuàng)建復(fù)旦大學(xué)神經(jīng)生物學(xué)研究所并任所長。 曾任中國生理學(xué)會理事長,亞太地區(qū)生理學(xué)聯(lián)合會第一副主席。長期從事視覺神經(jīng)機(jī)制的研究,在幾個(gè)層次上對視網(wǎng)膜中的信息傳遞的調(diào)控進(jìn)行系統(tǒng)研究并有數(shù)項(xiàng)新發(fā)現(xiàn)。1989年獲中科院自然科學(xué)一等獎(jiǎng),1991年當(dāng)選為中國科學(xué)院院士,2001年獲何梁何利科技進(jìn)步獎(jiǎng)?,F(xiàn)為Progress in Neurobiology等國內(nèi)外學(xué)術(shù)刊物編委或主編。,,根據(jù)所給的研究結(jié)果(確實(shí)有困難的同學(xué)可自選

3、一篇論文):1. 為該論文擬一個(gè)標(biāo)題并撰寫論文前言、材料和方法、結(jié)果、討論部分的概要(i.e. outline: 限前言不多于4句、材料和方法不多于5個(gè)標(biāo)題、結(jié)果不多于6句、討論不多于5句)。2. 為該論文選一個(gè)最適合的雜志,按照該雜志的投稿要求,以你的名義和通訊作者的身份給該雜志寫一封全真(除了不用郵寄給該雜志)的投稿信(cover letter),投稿信寫法可參照參考書和魯白教授的ppt.3.按照所投稿雜志的要求撰寫論文摘要(

4、可不做)(自選論文的同學(xué)請附所依據(jù)的論文全文)寫下你認(rèn)為最好的一個(gè)報(bào)告的報(bào)告人的名字(本學(xué)期最佳被告人).寫好姓名和學(xué)號打印,2006年1月4日前交西7號樓160/168陳曉青)。日后本作業(yè)所依據(jù)的論文全文和所發(fā)表的雜志等信息將上載到課程網(wǎng)頁上供大家參考.,作 業(yè) 二,科研論文撰寫和送審過程中導(dǎo)師和學(xué)生的互動(dòng),楊 雄 里,復(fù)旦大學(xué)神經(jīng)生物學(xué)研究所,本研究室科研論文撰寫的程序,導(dǎo)師和學(xué)生討論論文的基本構(gòu)思、框架、插圖;學(xué)生說明其實(shí)

5、驗(yàn)結(jié)果的創(chuàng)新點(diǎn);決定投寄何種雜志。學(xué)生向?qū)熖峁┡c該課題有關(guān)的主要綜述和原始論文(20~30篇)。由學(xué)生本人撰寫論文的初稿,送交導(dǎo)師。,導(dǎo)師對初稿作出評論;請學(xué)生補(bǔ)充實(shí)驗(yàn)數(shù)據(jù),并提出修改意見,但通常并不立即修改。參考導(dǎo)師評論和修改意見,學(xué)生撰寫第二稿,送交導(dǎo)師。導(dǎo)師在第二稿基礎(chǔ)上進(jìn)行修改,部分內(nèi)容完全重寫,交回學(xué)生,請學(xué)生提出修改意見(用不同字體標(biāo)明),形成第三稿。,本研究室科研論文撰寫的程序,導(dǎo)師與學(xué)生對第三稿進(jìn)行討論

6、后,由導(dǎo)師擬就第四稿,交回學(xué)生再評論和修改。對學(xué)生的評論和修改意見作認(rèn)真考慮后,擬就第五稿(半定稿),請學(xué)生評論、修改。導(dǎo)師最后定稿(第六稿),并對英文作仔細(xì)潤色。由學(xué)生嚴(yán)格按投寄雜志的要求整理定稿、送審。,本研究室科研論文撰寫的程序,雜志主編對送審論文的說明信(cover letter)四種類型,不作任何修改即表示接收。表示接收的意圖,但指出需作修改。不明確表示“ 收” 或“ 拒”。退稿。,From: &

7、quot;NeuroReport" To: Sent: Wednesday, June 18, 2003 6:19 PMSubject: NeuroReport: Decision on Voltage-gated K+ channel subunits on cholinergic and dopaminergic amacrine cells 18 Jun 2003 Dear Dr. Yang, Su

8、bmission no.: NR-D-03-00757 Article title: Voltage-gated K+ channel subunits on cholinergic and dopaminergic amacrine cells Corresponding author: Dr. Xiong-Li Yang Your paper has been seen by our reviewers and I hav

9、e received from the Section Editor a favourable recommendation. I am pleased to let you know that we will therefore publish it in the next issue of NeuroReport to be compiled. There is no specific criticism of the paper

10、and no requests of revision (and this makes a most pleasant and unusual change from our routine; congratulations!). A decision is not yet been made on the cover of the issue but we will take into consideration the fig

11、ure that you are offering for the purpose. If your picture is chosen (the chances are high), I will need an ad hoc figure legend, that could be read and understood without direct reference to the paper itself; it could b

12、e quite long, but it has to be extremely clear. Will you have a go at it?. Thank you for sending this interesting paper to our Journal. Kind regards. Yours sincerely, Giorgio Gabella, MD DSc Editor in Chief

13、 NeuroReport,Localization of Kv subunits in retinal amacrine cells Cholinergic Dopaminergic,Kv 3.1b,Kv 4.3,回復(fù)論文評審意見的程序,導(dǎo)師和學(xué)生對評審意見逐條進(jìn)行討論,決定如何答復(fù),是否需作補(bǔ)充實(shí)驗(yàn)。由學(xué)生擬出答復(fù)意見。,Zhang, D.Q. and Yang, X.L. (1998) GABA

14、 modulates color-opponent bipolar cells. Brain Res.,792:319-323.Lu, T. Shen, Y. and Yang, X.L. (1998) Desensitization of AMPA receptors on horizontal cells isolated from crucian carp retina. Neurosci Res., 31:123-135

15、.Shen, Y. and Yang, X.L. (1999) Zinc modulation of AMPA receptors may be relevant to splice variants in carp retina. Neuroscience Lett., 259:177-180.Shen, Y., Lu, T. and Yang, X.L. (1999) Modulation of desensitiza

16、tion at glutamate receptors in isolated crucian carp horizontal cells by concanavalin A, cyclothiazide, aniracetam and pepa., Neuroscience, 89:1979-1990.Zhang, D.Q., Yang, R. and Yang, X.L. (1999) Suppression of sust

17、ained and transient on signals of amacrine cells by GABA is mediated by different receptor subtypes. Science in China, Ser.C. 42:395-400.Zhang, J.and Yang, X.L.(1999) GABAb receptors in Muller cells of the bullfrog re

18、tina. NeuroReport, 10:1833-1836. Li, P., Yang, X.L.(1999) Zn2+ differentially modulates glycine receptors versus GABA receptors in isolated carp retinal third –order neurons . Neuroscience Lett., 269:75-78.Han, M.H.

19、 and Yang, X.L. (1999) Zn2+ differentially modulates kinetics of GABAc vs GABAa receptors in carp retinal bipolar cells. NeuroReport, 10:2593-2597.Yang, X.L. Gao, F. and Wu, S.M. (1999) Moduation of horizortal cell

20、function by GABAa and GABAc receptors in dark-and light-adapted tiger salamander retina. Visual Neuroscience. 16:1-13.,Publications (1998~Present ),,Yang, X.L. Shen, Y., Han, M.H. and Lu, T. (1999) Physiological and Pha

21、rmacological Characterization of Glutamate and GABA Receptors in the Retina. Korean Journal of Physiology and Pharmacology, 3:461-469.Du, J.L. and Yang, X.L. (1999) Retinal bipolar cell——A model for the study of neuro

22、nal signal integration . Chinese Science Bulletin. 44:1737-1743.Yang, X.L., Shen, Y. and Han, M.H.(1999) Glutamate and γ-aminobutyric receptors and their characteristics in retina. Chinese Science Bulletin, 44:1548-1

23、556.Yang, X.L. Gao, F. and Wu, S.M.(1999) Modulation of horizortal cell function by GABAa and GABAc receptors in dark-and light –adapted tiger salamander retina. Visual Neuroscience.1-13.Shen, Y., and Zhou, Y. and Y

24、ang, X.L. (1999) Characterization of AMPA receptors on isolated amacrine-like cells in carp retina. Eur.J.Neurosci., 11:4233-4240. Xu, H.P. and Yang, X.L. (1999) Differential modulation by GABA of signals from red –

25、and green –sensitive cones in the carp retina. Brain Res Bul ., 51:493-497. Zhao, J.W., Du, J.L., Li, J.S. and Yang, X.L.(2000) Expression of GABA transporters on bullfrog retinal Müller cells . Glia 31:104-117

26、Du, J.L. and Yang , X.L .(2000) Subcellular localozation and complements of GABAA and GABAc receptors on bullfrog retinal bipolar cells. J. Neurophysiol., 84:666-676,Xu, H.P., Zhao, J.W. and Yang, X.L. (2003) Choliner

27、gic and dopaminergic amacrine cells differentially express calcium channel subunits in the rat retina. Neuroscience, 118: 763-768.Tian, M., Chen, L., Xie, J.X., Yang, X.L. and Zhao, J.W. (2003) Expression patterns of i

28、nwardly rectifying potassium channel subunits in rat retina.  Neurosci Lett., 345: 9-12.Tian, M., Xie, J.X., Zhao, J.W. and Yang, X.L. (2003) Differential expression of voltage-gated postssium channel subunits on

29、cholinergic and dopaminergic amacrine cells in rat retina. NeuroReport,14:1763-1766Li, G.L. and Yang, X.L. (2003) Glycinergic input to carp retinal ganglion cells may be mediated by glycine receptors with homologous ki

30、netics.  Brain Res.,991:171-179Shen, Y. Zhang, A.J. and Yang, X.L. (2003) Uncoupling of horizontal cells alters the receptive fields of retinal bipolar cells. NeuroReport, 14:2159-2163Huang, H., Luo, D.G., Shen,

31、 Y., Zhang, A.J., Yang, R and Yang, X.L.(2004) AMPA receptor is involved in transmission of cone signal to ON bipolar cells in carp retina. Brain Res., 1002:86-9340. Huang, H., Luo, D.G., Shen, Y., Zhang, A.J., Ya

32、ng, R and Yang, X.L.(2004) AMPA receptor is involved in transmission of cone signal to ON bipolar cells in carp retina. Brain Res., 1002:86-9341. Yang, X.L., (2004) Characterization of receptors for glutamate and

33、 GABA in retinal neurons. Progress in Neurobiology. 73:127-150,Du, J. L., Yang, X. L. (2002) Bullfrog retinal bipolar cells may express heterogeneous glycine receptors at dendrites and axon terminals. Neuroscience Letter

34、s 322: 177-181.Yang, X.L., Fan, G and Wu, S.M. (2002) Non-linear, high-gain and sustained –to-transient signal transmisson from rods to amacrine cells in dark-adapted retina of Ambystoma. J. Physiol., 539: 239-251.

35、Du, J. L., Yang,X. L. (2002) Glycinergic synaptic transmission to bullfrog retinal bipolar cells is input-specific. Neuroscience, 113: 779-784.Xu, H.P., Zhao, J.W., Yang,X.L. (2002) Expression of voltage-dependent c

36、alcium channel subunits in the rat retina. Neurosci. Lett 1.   329:297-300.Luo, D.G., Li, G.L and Yang, X.L (2002) Zn2+ modulates light responses of color-opponent bipolar and amacrine cells in the carp reti

37、na. Brain Res. Bull., 58:461-468.Xu, H. P., Yang, X. L. (2002) Different effects of low Ca2+ on signal transmission from rods and cones to bipolar cells in carp retina. Brain Res., 957:136-143.Luo, D. G., Yang, X.

38、L. (2002) Suppression by zinc of transient OFF responses of carp amacrine cells to red light is mediated by GABAA receptors. Brain Res., 958:222-226.Du, J.L., Xu, L.Y.,and Yang, X.L. (2002) Glycine receptors and transp

39、orters on bullfrog retinal Müller cells. NeuroReport. 13:1653-1656.,42. Cao, L.H., Yu, Y.C., Zhao, J.W., and Yang, X.L. (2004) Expression of natriuretic peptides in rat Muller cells. Neurosci. Lett. 36

40、5:176-17943. Chen, L., Yu, Y.C., Zhao, J.W and Yang, X.L* (2004) Inwardly rectifying potassium channels inrat retinal ganglion cells . Eur. J. Neurosci., 20:956-96444. Liu, J., Zhao, J.W., Du, J.L and

41、 Yang, X.L.(2005) Functional GABAB receptors ate expressed at the cine photoreceptor terminals in bullfrog retina. Neurosci. 132: 103-113 45. Lee, S.C., Zhong, Y.M and Yang, X.L. (2005) Expression of glycine recep

42、tor and transporter on bullfrog retinal Muller cells. Neurosci. Lett. 387:75-79.46. Shen, Y., Chen, L., Ping, Y. and Yang, X.L. (2005) Glycine modulates the receptive field center response of ON type rod-dominant b

43、ipolar cells in carp retina. Brain Res. Bull. 67:492-497.47. Huang, H., Lee, S. C. and Yang, X.L.(2005) Modulation by melatonin of glutamatergic synaptic transmission in the carp retina. J . Physiol. 569:857-871.

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