急性腦梗死患者血清瘦素、IL-6水平及其相關(guān)性研究.pdf

1、山西醫(yī)科大學(xué)碩士學(xué)位論文急性腦梗死患者血清瘦素、IL6水平及其相關(guān)性研究姓名：王黎申請(qǐng)學(xué)位級(jí)別：碩士專業(yè)：神經(jīng)病學(xué)指導(dǎo)教師：劉瑞珍20050515山西陛科大學(xué)硬士學(xué)能論文Associationandthelevelsofieptin，interleukin6(IL6)inserumofacutecerebralinfarctionpatientAbstractobjective：toexplorethelevelsofLeptinint

2、edeukin一6(1I。一6)inserumofacutecerebralinfarctionpatientandtheassociationofLeptinlevelwithIL一6、bloodpressure，bloodfatandfibrinogen，andtOinvestigatetheroleoftheserumLeptinIL一6inpatientswithcerebralinfarction(CI)Methods：the

3、selLlmconcentrationofleptinandIL一6in60patienswithCI，40healthycontrolsweremeasuredbymeansofradioimmunoassayandtOmeasurethebloodpressureandtheserumconcentrationofthebloodfat，fibrinogenandtOanalysistheassociationoftheseinde

4、xesResult：comparedwiththoseinthecontrols，therewereelevationofgerlnnleptinlevel(P005)andIL6level(P001)TheserumleptinlevelrelatedpositivelytOtheleveloftheIL一6(r=0512，PO01)andtheLDL(r=0453，P001)，thetotalcholesterol(FO326，P0

5、01)，thetriglyeride(r=O435，P0叭)，thebloodpressure(r=O313P005)relatednegativelytotheHDLlevel(r：一0262，P005)ThereisnelmionbetweentheleptinandthefibfinogeninthepatientswithCIConclusion：theelevationofserulnleptinlevelandtheover

6、expressionofIL6iStheappearanceofneuroendoerinefunctionaldisorderinthepatientswithacutecerebralinfarctionThelevelofleptinhadcloserelmiontoIL一6andrelatedcloselytOtheriskfactorsofeerebrovasculardiseaseLeptinandIL6participat