新型三角架配體的合成、表征及其性質(zhì)研究.pdf

1、南開大學(xué)碩士學(xué)位論文新型三角架配體的合成、表征及其性質(zhì)研究姓名：王旭申請(qǐng)學(xué)位級(jí)別：碩士專業(yè)：物理化學(xué)指導(dǎo)教師：林華寬2000.5.1ABSTRACTThetripodalligands，whichextendinthreedirections，possesslowsymmetryThecorrespondingcomplexesplaya11importantroleinmodellingenzymeandtheoryofcoordin

2、ationchemistryAdditionallythereiscontinuinginterestinthechemistryofruthenium，primarilyduetothefascinatingelectrontransferandenergy—transferpropertiesTherefore，inthisthesis，weareinterestedindesigningandsynthesizingsomehov

3、eltripodalligandsThemaincontributionsareasfollows1)Startingfrom13，5benzenetricarboxaldehyde，fivenewtripodalligandshavebeenpreparedAllligandswereeharacterizadbyelementalanalyses，IR，‘HNMR2)Bypotentiometrictitrationmethod，t

4、heprotonationconstantsoftheligandLAl，LA2，LA3and5Rphenin80％DMSO(VⅣ)aqueoussolution，thestabilityconstantsoftherespectivemetalions、ⅣitllLA2LA3andsubstituteddioxotetraaminemacrocyclebinarycomplexeshavebeendeterminedAdditiona

5、llythestabilityconstantsoftherespectiveCu(U)5RphenbinarycomplexeswimLA2LA3havebeendeterminedaswell，andthestabilityconstantsoftheCo(II)andrespective5Rphenternarycomplexeswithsubstitueddioxotetraarninemacrocyclehavebeendet

6、ermined31AnewcomplexofRuphenoxunitwimadioxotetraminederivativeissynthesizedandcharacterizedbyelementalanalysisand瑯Withadditionofthedifferentmetalions，thefluorescencequenchingphenomenaofRu(II)complexwereobservedatdifferen

7、tpHvalueTheprobablemechanismoffluorescencequenchingwasproposedandexplmned4)Tomodelactivesitestructureofcabonicanhydrase(CA)，activityofthecomplexesCu(H)‘LA3andZnLA3incatalyzingthedecomposingreactionofHC03’werestudiedusing

8、stoppedflowspectrophotometerExperimentalresultswerediscussedandaresonablereactionmechanismwasproposed5)Usingethidiumbromideasafluorescenceprobe，theinteractionofthecorrespondingLa(III)豇aminoacidcomplexeswithcalfthymusDNAw