β-TCP植入對拔牙后剩余牙槽嵴保存影響的實(shí)驗(yàn)研究.pdf

1、新疆醫(yī)科大學(xué)碩士學(xué)位論文β-TCP植入對拔牙后剩余牙槽嵴保存影響的實(shí)驗(yàn)研究姓名：馬瑩申請學(xué)位級別：碩士專業(yè)：口腔臨床醫(yī)學(xué)指導(dǎo)教師：何惠宇2009-04新疆醫(yī)科大學(xué)醫(yī)學(xué)碩士學(xué)位論文 —2—Experimental study on the impact of immediate implantation of ß - Tricalcium phosphate on alveolar ridge defec

2、t Postgraduate:Ma Ying Supervisor: Associate Professor HeHuiyu Abstract Objects: To establish a rabbit animal model of alveolar ridge defect after tooth extraction,and to evaluate the impact of imme

3、diate implantation of ß - tricalcium phosphate on preventing the residual alveolar bone. Methods : Under the general anesthesia, the bilateral central incisors of rabbits were extracted, and &

4、#223; - TCP was implanted immediately on one side as the experimental group, while the other side without implantion as control. Rabbits were killed after 4,8 and 12 weeks.The length, width, he

5、ight changes of extraction area of both sides were measureed by Vernier caliper .The change of trabecular bone were examined by X- ray . The interface between ß - TCP and the alveolar bone

6、 were observed by Scanning electron microscopy . The density of residual ridge was detected by Dual- energy X - ray Absorptiometry . The histopathological changes of the alveolar bone were observed on

7、 the HE staining.Result: The width of alveolar ridges was significant different between the experimental group and the control group after 4week,8 week and 12 week after ß - TCP implantatio

8、n（P﹤0.05）.The length of alveolar ridge was significantly different at 8 week and 12week after implation （P﹤0.05）. The height of alveolar ridge was significantly different at 8 week and 12week aft

9、er implation （P﹤0.05） .The amount of trabecula bone of experimental group were more than that of the control group showed by X- ray photography. The alveolar bone and ß - TCP combined closel

10、y under scanning electron microscope; The density of bone scan showed it was significantly different （P﹤0.05）between the experimental group and control group. Histopathological observation showed t

11、hat 4w after extraction,bone mass was increasing markedly in the alveolar fossa,the deposition of new bone was continued,vascular network became sparse.8w,new bone grow persistently.12w, the entire

12、 alveolar fossa was filled with new trabecular bone,the small vascular network was as the rule,new bone was growing mature, the boundaries between new bone and the alveolar bone is not clear.