妊娠期及妊高征滋養(yǎng)細(xì)胞E-鈣粘附素的表達.pdf

1、上海第二醫(yī)科大學(xué)碩士學(xué)位論文妊娠期及妊高征滋養(yǎng)細(xì)胞E鈣粘附素的表達姓名：史宏申請學(xué)位級別：碩士專業(yè)：婦產(chǎn)科學(xué)指導(dǎo)教師：戴鐘英2001.4.1樸ieE甲essi加JEcadherin叭“Mai陣翔iancyof記n州吻喇口招匕p婦AbstractThespiralarteriesofuterushavesomephysiologicalchangesduringnormalpregnancy.Thesechangesareduetothe

2、invadingofcytotrophoblasticcells.Inpreeclampsiatheinvasiveabilityofcytotrophoblasticcellsisimpaired.Inthisstudyweuseimmunohistochemicaltechniquetostain40cases.AllthecytotrophoblastsofvillihavestrongpositiveEcadherinstain

3、ingafter10weeksofpregnancy.Incytotrophoblasticcolumnthestainingbecameweakergraduallyfromtheproximitytothedistance.Inthesecondtrimesterextravilloustrophoblasts(E四almoststainnegative.InthethirdtrimesterthecolorationoftheEV

4、Tbecamestrongerthanthatinthesecondtrimester.InpreeclampsiathecolorationofEVTisnotasdistinctasthenonpreeclampsiacasesduringthesametrimesterandthepercentageofpositivecellsinpreeclampsiaandnonpreeclampsiaare27.45%and12.74%r

5、espectively.Thereiss心nificantdiferencebetweenthetwogroups(p0.01).ThelossandoraberranceoftheexpressionofEcadherininEVTcanenhancetheirinvasiveability.Inpreeclampsiathefadingof伽expressionisnotdistinctsotheabilityofinvasioni