VEGF-C、FLT-4和cPKC在肺癌中的表達及意義.pdf

1、延邊大學碩士學位論文VEGFC、FLT4和cPKC在肺癌中的表達及意義姓名：于浩申請學位級別：碩士專業(yè)：病理學與病理生理學指導教師：金仁順20070430延迭大學醫(yī)學豁硬七學位論文ExpressionandsignmcanceofVEGF—C、FI』r4andcPKCinIungcancerABSTI認CTobjective：：1’0investigate山eexpressionofVEGF—C，Fu乙4andcPKCinlungcaf

2、IceraIld乜rcIationshipwithcIinicopathologkalfeatLIresMethod：ExpressionofVEGF—℃、FI。T4andcPKCwasdetectedbyimunohistochemiScalSPmetllodmninetythfeec器esofIungcancerttheresults、張fecomparedanay髓dwiththecIinicopathoIogicfeatufes

3、oflungcancerResuol、Theexp他ssionmteofVEGF—C、FU’一4卸dcPKCwere731％、624％and292％iIIIungcarlcef，咒spectiVely2、ThepositiverateofVEGF—Cw笛759％，733％msquamouscellcarcinomaandadenocarcinoma，anditw船6O％insmallcelllungcancer(SCLC)，咒spect

4、iveIyTherewassignincantlyd汀ferencebetweennon—smaUcell(SCLC)andSCLC(PO05)TheexpressjonrateofVEGF—Cwasnodift’erencebet、veenthedegreeofdi腩rentiationandTNMstages，ajlditw硒733％and444％inlymphnodesmetaStasis(LNM)卸dnon—Iy唧hnodcsm

5、etaStasis(NLNM)(P005)3ThepositiverateofFLT4was345％，339％insquamouscellcarcinomaandadenocarcinoma，andonlyonecaseofSCLCwaspositiveexpressionTheexpressionrateofFU’一4w酩nodifferencebetweenthedegreeofdⅢ’erentjatjonandTNMstages，

6、“was351％t194％iJlLNMandNLNM(PO05)4The∞s“iverateofcPKCwas724％、712％and824％inSquamouscellc缸cinoma，adenocarcmor【IaandSCLC，respectiveLyTheexpressionrateofFL丁一4wassign訊cantlydiffb陀nceamongthede鱸eeofdm’e陀ntiation，TNMstagesandLNM