生元丸治療尋常型銀屑病血熱證及與SP、TNF-α的相關(guān)性研究.pdf

1、陜西中醫(yī)藥大學(xué)學(xué)位論文原創(chuàng)性聲明及使用授權(quán)聲明學(xué)位論文原創(chuàng)性聲明本人鄭重聲明：所呈交的學(xué)位論文，是個(gè)人在導(dǎo)師的指導(dǎo)下，獨(dú)立進(jìn)行研究工作所取得的成果，無抄襲及編造行為。除文中已經(jīng)特別加以注明引用的內(nèi)容外，本論文不含任何其他個(gè)人或集體已經(jīng)發(fā)表或撰寫過的作品成果。對(duì)本文的研究做出重要貢獻(xiàn)的個(gè)人和集體，均已在文中以明確方式標(biāo)明并致謝。本人完全意識(shí)到本聲明的法律結(jié)果并由本人所承擔(dān)的法律責(zé)任。學(xué)位論文作者簽名(需親筆)墊壘碴Et期：勱眵年S月西日關(guān)

2、于學(xué)位論文使用授權(quán)的聲明陜西中醫(yī)藥大學(xué)有權(quán)保留使用本人學(xué)位論文，同意學(xué)院按規(guī)定向國家有關(guān)部門機(jī)構(gòu)送交論文的復(fù)印件和電子版，允許被查閱和借閱。本人授權(quán)陜西中醫(yī)藥大學(xué)可以將本學(xué)位論文的全部或部分內(nèi)容編入有關(guān)數(shù)據(jù)庫進(jìn)行檢索，可以采用影印、縮印或其他復(fù)印手段保存和匯編本學(xué)位論文?？梢怨?包括刊登)論文的全部或部分內(nèi)容。保密口，在一年解密后適用本授權(quán)書。本學(xué)位論文屬于不保密回。(請(qǐng)?jiān)谝陨戏娇騼?nèi)打“4”)論文作者簽名(需親筆)整壘魚El期：枷1歹

3、年歹El7／5Et論文導(dǎo)師簽名(需親筆亡坼日期：吲r年l＼馬r日L／人TheinfIuenceofTNFQ、SPintheserumofpatientswithpsoriasisvuIgarisbyshengyuanwanAbstractObjective：Thepurposeofthisstudywasthattoobservetheclinicalefficacyofshengyuanwan，whichcancurepsoriasi

4、svulgarisheatbloodtype，wealsoobservedthecontentsofSubstancePandTNF—Qbeforeandafterinbloodofpatients，whicheffectedbyshengyuanwanThenumberofpsoriasisvulgarisis30Afterthat，WewanttodiscussthefeasiblemechaniSillofaction，becau

5、sethatweintendtofurnishsometheoreticalbasisonclinictreatmentMethodA1140patientsselectedcamefromDermat0109ydepartmentofThecollegeAffiliatedhospita]oftraditionalChinesemedicineofshaanxi，fromApril2014toJanuary2015Theywerede

6、tectedthatwithpsoriasisvulgarisbloodheattypeThe40patientswererandomlydividedintoexperimentalgroupandtreatmentgrouponegroup(shengyuanwangroup)20cases，controlgroup(xiaoyinke1i)20cases，andthenselected20healthysubjectsthecen

7、terphysicalexaminationofThecollegeAffiliatedhospitaloftraditionalChinesemedicineofshaanxiAfterthetest，therewasnosignificantdifferencebetweengroupswithstatisticalsignificanceTakeacomDrehensivetreatmenttherapyandsShengyuan

8、wansixgram／time，threetimes／dayXiaoyinke1ionebag／time，threetimes／dayDuringtheperiodofkeepinginhospital，Groupswithgeneralwesternmedicine(10ratadine)andNB—UVBraysphototherapy，topicalfivepercentsulfurointment，treatmentafterd

9、ischargeamountoftheexperimentalgroupandcontrolgroupdrugs，dietacrimonystimulationfoodduringtreatmentAlaparoscope，usuallyconnectedtoa4weeksasatreatmentcycle，2treatmentcycleObservepatientswasdetectedbeforeandaftertreatment，

10、thetreatmentgroupinhospitalandthreeweeksafterthetreatment，extractionofperipheralvenousblood，usingenzyme—linkedimmunoassay，wereobservedbeforeandaftertreatmentofsubstanceP，thelevelofTNFalphachanges，andin20caseshealthycontr

11、olgroupResults：thetreatmentgroupcurerate1500％，totaleffectiverate7500％，controlgroupcurerate100％，totaleffectiverate6500％，theciinicalcurativeeffectoftreatmentgroupisbetterthanthatofcontrolgroup，comparedtwogroupshaveobviousd

12、ifferenceSubstancePgroupaftertreatment，theTNFalphalevelsignificantlydecreased，butstillhigherthanthehealthycontrolgroup，withsignificantdifferencebeforeandafterConclusionshengyuanwanpilltreatmentpsoriasiseffectisremarkable

13、，theeffectisbetterthanthatofsilverparticlesPatientswithpsoriasisinserumSubstanceP，TNF—Qlevelhigherthanthatofnormalpeople，aftertreatmentthanbeforetreatmentSignificantlydecreasedPossiblepathwaysthroughregulatingthesecretio