Comparison of clinical characteristics of Kawasaki disease by age spectrums in children.pdf

1、Background:The aim of this study was to compare the clinical characteristic of Kawasaki disease by age spectrums in children at First Affiliated Hospitals of Xinjiang Medical University. Patients and methods:202 patients

2、 with Kawasaki disease hospitalized from 2002–2012 in the Department of Pediatrics at First Affiliated Hospitals of Xinjiang Medical University. The data was collected by reviewing medical record. The disease was diagnos

3、ed on the basis of clinical characteristics. The patients were divided into twogroups, group A (<5 years old) and group B (>5 years old).Results:Out of 202 Kawasaki disease patients, 143 (70.8 ％) were in group A, male we

4、re 88 (61.53%) female 55 (38 .46%), male to female ratio was 1.6:1. 59 (29.2%) patients were in group B, malewere 49 (83.05%) female 10 (16.95%), male to female ratio was 4.9:1. The most common clinical features in both

5、groups were fever and lip fissuring, 136 (95.10 %) and 79 (55.24%) in group A, 55 (93.22 %) and 30 (50.84%) in group B. Laboratory findings suchas white blood cells, platelets, erythrocyte sedimentation rate and c-reacti

6、ve protein were high in group A, hemoglobin and albumin were high in group B. Coronary artery dilatation was 22 (15.4%) and coronary artery aneurysm was 5 (13.5%) in group A but 7(11.9 %) and 1 (1.7%) in group B. Chinese

7、 patients were more in both groups i.e 125 (87.41%) in group A and 50 (84.74%) in group B, Uygur minority were 10 (6.99%) in group A and 4 (2.79) in group B, other minorities were 9 (6.29%) in group A and 6 (10.16%) in g

8、roup B.Conclusion:In this study, the most common clinical features were fever and lip fissuring in both groups, group A and group B but the ratio was high in group A, followed by other clinical features. The coronary art

9、ery dilatation and coronary artery aneurysm were high in group A as compare to group B. Chinese patients were more as compare to other minorities. This study may be an underestimate and large scale prospective studies ar