影響124例星型細(xì)胞腫瘤預(yù)后的臨床多因素分析.pdf

1、中南大學(xué)碩士學(xué)位論文影響124例星型細(xì)胞腫瘤預(yù)后的臨床多因素分析姓名：徐斌初申請(qǐng)學(xué)位級(jí)別：碩士專(zhuān)業(yè)：外科學(xué)指導(dǎo)教師：袁賢瑞20070501碩士學(xué)位論文英文摘要ABSTRACTAimTodiscussingtheclinicpmgnosticmarkersaboutastrocytetumors，supplyingthechoiceofclinictreatmentsandpredictingthepatientsprognosticou

2、tcomeMethodsThemedicaldataof124caseswithAstrocytictumours，whichwereadmitedtothedepartmentofneurosurgery，Xiangyahospital，wereanalyzedbyunivariateandmultivariateanalysesTheKaplanMei日method，LogranktestandtheCoxregressionmod

3、elwereusedtoanalyzetheprognosticfactorResults(1)Generalinformation：Therewere124patientsinthefollowupteamAtamedianfollowupof32monthsPatient’Smeanageatdiagnosiswere3332yearsTherewere73men(589％1and5l(411％1womenThedurationso

4、fsymptomswas4daysto30years(mean274months)ThePSTandoverallsurvivalat3、5yearswere：7912months、762％and60A％whichwere9155months、835％and716％inLGGs，butthePSTandsurvivalwereonly3868monthsand384％inHGGs；(2)Onunivariateanalysis：thef

5、ollowingfactorshavefavorableinfluenceonPST：age40、totalorsubtotaltumorresection、lowgradehistology、positionofventricleButsex、seizure、volume、scoreofKPS、surgerypluspostoperativeradiotherapyand(or)chemotherapymayhave110relati

6、ontothepatientsprognosticoutcome(3)Onmultivariateanalysisonlyextentofresection、histologicalgrade、ageanddurationofsymptomsbeforediagnosisretainedsignificanceConclusion(1)thisteamhasbetterprognosticoutcome；(2)NotonlyLGGsbu

7、talsoHGGs，surgeryiSthefirstchoice；(3)Patientswithtotalresectionpossibly、lowhistolo#calgrade、age40andlongerdurationofsymptomsbeforediagnosishavebetteroutcome；(4)positionofventriclemayhavebetteroutcome；KeywordsAstrocytictu