胃癌中雄激素受體、RB、CyclinD-,1-的表達及其相關(guān)性研究.pdf

1、安徽醫(yī)科大學碩士學位論文胃癌中雄激素受體、RB、CyclinD的表達及其相關(guān)性研究姓名：錢結(jié)勝申請學位級別：碩士專業(yè)：外科學指導教師：劉弋王光升2000.6.1胃癌中雄激素受體、RB、CyclinD。的表達及其相關(guān)性研究ExpressionofAndrogenReceptor、RB、CyciinDlintheGastricCarcinomaandtheirrelationshipsAbstract：Objective：Tostudyth

2、eexpressionofandrogenreceptor、RB、CyclinDlingastriccancerandtherelationshipsamongthemMethod：Immunohistochemical(SP)methodwasusedtodetecttheexpressionofandrogenreceptor、RB、CyclinDlinthetissuesofgastriccancerResults：(1)Of59

3、caseofgastriccarcinoma，positiverateofAR、RBandCyclinDlseparatelyare475％(28／59)、695％(41／59)、475％(28／59)：andaresignificantlyhigherthanthatofadjacentnon—tumoroustissue(2)AsignificantlypositivecorrelationbetweenARandRbwasfoun

4、dingastriccanceratfirsttime(3)TheexpressionofARandRBwasstatisticallysignificantdifferentbetweenbigtumor(3cm)andsmallone；asignificantpositirecorrelationbetweenRBandmetastasiSoflymphatiCnodewasalsodetectedingastriccancerCo

5、nclusion：(1)OverexpressionofAR、RB、CyclinDlweredetectedingastriccancerandwerecloselyrelatedtotheformationanddevelopmentofgastriccancer(2)ApositivecorrelationbetweenARandRBsuggestthatARandRBaresynergictopromotetheformation