一氧化氮參與的a、β不飽和酮的硝化反應(yīng)及環(huán)氧酮開環(huán)反應(yīng)的研究.pdf

1、蘭州大學(xué)博士學(xué)位論文一氧化氮參與的a、β不飽和酮的硝化反應(yīng)及環(huán)氧酮開環(huán)反應(yīng)的研究姓名：李銳申請(qǐng)學(xué)位級(jí)別：博士專業(yè)：化學(xué)、有機(jī)化學(xué)指導(dǎo)教師：吳隆民20070501AbstractInthisdissertation，1willrepresentmystudiesonthenitrationofChalconederivatives，reactionofepoxideketone，andthearomatizationof35一disubs

2、titued2isoxazolineswithnitricoxide@0)Theprincipalresultsareexpressed鸛follows1ThenitrationofchalconederivativeswithNOoccurredhighlystereoselectivelyuniquelyaffordingE—a—nitro—propenonesingoodyieldThereactionismostlikelyin

3、itiatedbyelectrophilicadditionofNOtotheC—CdoublebondspecificallyattheapositionItprovidesanewapproachforpreparinganitrochalconederivativesdirectlyfromchalconederivativesusingNOIthastheadvantageofhighsteroselectivityavaila

4、blestartingmaterialsandconvenientperformanceundermildconditionsProductsgallbeusedinthesynthesisofheterocyclecompounds2TheringopeningreactionofepoxyketoneswithNOindichloromethaneaffordstheC一3ringopenedproducts，erythro—ahy

5、droxylnitratesinahighlysyn—selectivemannerNeactionoccurredwhenthesystemwasabsolutelyprotectedfromairThereactionisassumedtobeinitiatedbyN02WhenthereactionWasperformedinprotoniesolvent，suchasmethanol，allanti—methoxylhydrox

6、ylcompoundWasobtainedasthemainproductItappearedthatthereactionwascontrolledbysolvent33，5一disubstituted2isoxazolineswereoxidizedtocorrespondingisoxazolesbyNOindichloromethnneThereactionmorelikelyoccurredviaaoneelectrontra