辛辣食物對咪唑烷基脲皮膚刺激性影響.pdf

1、分類號密級UDC學(xué)號200502107延邊大學(xué)碩士學(xué)位論文辛辣食物對咪唑烷基脲皮膚刺激性影響ResearchonEffectsofSpicyFoodstoEpidermisStimulationofIazolidinylUrea研究生姓名劉楠培養(yǎng)單位延邊大學(xué)附屬醫(yī)院指導(dǎo)教師姓名、職稱金哲虎教授學(xué)科專業(yè)外科學(xué)研究方向化妝品皮炎論文提交日期2008年4月25日延邊大學(xué)碩士學(xué)位論文IIAbstractObjective:Cosmeticsan

2、tisepticistheimptantreasonofcosmeticsdermatitis.Indertoavoiddermatitisallergicreactionstherearemaximalconcentrationsfdifferentcosmeticsantiseptics.Recentresearchhadshownthatspicyfoodscouldenhancethebodylocalreactions.Pre

3、sentresearchisaimedtostudytheeffectsofspicyfoodsonepidermisstimulationinducedbyiazolidinylureaacommonlyusedcosmeticsantisepticsoastoprovidethedatafthediagnosistreatmentofrelateddiseases.Methods:Indertoinducetherabbitmode

4、l10%pepperfluid(10mlkgweight)alcohol(2.0gkgWeight)pepperalcoholmixture(5ml2.0gkgweight)wereusedtofillthestomachofrabbitsonceadaysalinewasusedascontrol.After7daysrabbits’symptomwasobservedsced.Everygroupwasdividedintosing

5、leskinstimulationtestsmultipleskinstimulationtestswithintegralinjuredskin.0.6%iazolidinylureawasappliedontheskinoncefsingleskinstimulationtestsonceadayf7daysfmultipleskinstimulationtests.24hlatergeneralhistologicalreacti

6、onswereobservedsced.Results：Comparedwithcontrolpepperalcoholmixturecouldallinducesymptomofspicyfoodsstimulationthescealsoincreasedprogressively.Theresultsofsingleskinstimulationtestsshowedthatgroupalcoholmixturehadmildsk

7、inirritationwithinjuredskinaveragehistologicalsces0.752.5respectively.Thereisobviousdifferencecomparedwithgroupcontrolpepper.Theresultsofmultipleskinstimulationtestsshowedthatgroupalcoholmixturehadmildmoderateskinirritat

8、ionwithintegralskinrespectivelywithaveragehistologicalsce2.04.5.Thereissignificantdifferencecomparedwithgroupcontrolpepper.Grouppepperalcoholmixturehadmildmoderatesevereskinirritationwithinjuredskinrespectivelywithaverag

9、ehistologicalsce0.758.2513.0.Thereissignificantdifferencecomparedwithgroupcontrol.Thereisobviousrelationbetweengeneralhistologicalscesstomachheatsyndromesces.Conclusion:Withthedoseusedinpresentstudypepperalcoholpepperalc

10、oholmixturecouldallinducespicyfoodsstimulationsyndromeinrabbitssuccessfullythedegreesincreasedprogressively.Hotstimulationcouldobviouslyenhancetheepidermisstimulationofiazolidinylurea.Weshouldconcernaboutthisinclinic.Key