山仙顆粒對S180肉瘤細胞轉染的昆明小鼠BCL-2和BAX基因表達影響的實驗研究.pdf

1、學院代號。，∞716●。___●_。___^_●__●_●___●_______一專業(yè)代碼；；i00802學號003121401039密級：1i|『jj。?！圯耲j毫◆薯陜西中醫(yī)攀，院ShaanxiUniveI_sity0fChineseMedicihe碩士學位論文山仙顆粒對SiS0肉瘤細胞轉染的昆明i小膩————————————●—————————————————————————__——_■上—一——BCL2和BAX基因表達影響的實驄

2、研究j!每i黻申請人?！?，慧矗、，，?！甶!；孵≯名i稱申謹。學穰類型一‘指導教一師i姓。名史迎莉中西醫(yī)結合舔床t專業(yè)學位陳光偉主任醫(yī)師n。o一?！觥鯻：■——_—’——論文提一一京。雕斯薯。黔。露澎006年5雕“r鞲饕爹——————～Title：TheexperimentalresearchwhichShanXianGranuleeffectedtheexpressionofBcl2andBaxinkungmingmicetrans

3、ferredbySarcoma180eel1ABSTRACTobjectiv：TOinvestigatethelevelofBcl2andBaxinKungmingmicetransferredbySarcoma180cell，andtoexplaintheanti—growthofthemalignanttumoroftheShanXianOranule(SXG)Method：40miceweredividedinto4groupsr

4、andomlyAwastheblankcontrastgroup，andB，C，DweremadeintomodelgroupsThenextdayaftermakingmodel，eachofC，DgroupsweregivenJinLongCapsule(JLC)andSXGseparatelyandA，Bgroupswerenormalshine21dayslater，weputthosemicetodeath，thendetec

5、tedthelevelofbcl一2andbaxbyusingirnmunothistochemicalmethodintransplantedtumorofS180cellAtthesanletimetesttheothertargetsResult：Thetimeofthetunlorcomingintobeing，theweightofthetransplantedtBmorandmice，thelevelofBel一2andBa

6、xintransplantedtunlorofC，DgroupsincontrastofthoseofBgroup，thedifferenceWasprominent(pO05)Conclusion：SXGcallresistthegrowthofS180SarcomaIt、SmechanismofresistinggrowthmostcorrelatewimlowingthelevelofBcl2andincreasingexpres