醫(yī)學免疫學-雙語課程教學大綱

1、《醫(yī)學免疫學雙語》課程教學大綱課程編號：25121009課程類別：學科基礎課程授課對象：本科生開課學期：第4學期學分：2學分主講教師：王泳等指定教材：TextbookofMedicalImmunology醫(yī)學免疫學（雙語版TristramG.Parslow譚錦泉姚堃主編科學出版社）教學目的：MolecularImmunologyisthebasiccourseofbiotechnologyspecialty.Thiscoursemain

2、lyintroducesthebasicprinciplesknowledgeofinnateadaptiveimmunityfromthebeginningoftheintroductionofcellsgansoftheimmunesystem.Thecontentsincludeasfollows:antigenantibodyimmunoglobulinMHCdevelopmentofTBcellscellularimmuner

3、esponsehumalimmuneresponsecytokinestheirreceptstransplantationimmunologyhypersensitivitytumimmunology.ThekeycontentistheAgspecificimmuneresponsesofTBlymphocytes.Multimediateachingmethodiscombinedwiththeillustrationbywdwh

4、ichcouldgivethestudentsthelivingcomprehensionofthetheeticalknowledgemakethemgraspthebasictheyknowledgeprincipleofimmunologysystematicallybuildasoundbaseftheirfurtherstudy.第一章FundamentalsofImmunology&第二章BriefHistyProspect

5、ofImmunology課時：1周，共3課時教學內容第一節(jié)ImmunityImmunecells一、Grasptheconceptofinnateimmunityadaptiveimmunity.二、Comprehendthepropertiesoftwomainphagocytecellsincludingtheneutrophilsthemonocytemacrophagesystem.三、Comprehendthetwomajli

6、neagesknowasTcellsBcells.四、KnowthreemajclassesofcellsfunctioningasAPCsincludingdendriticcellsmacrophagesBcells.五、GrasptheconceptofNKcells.第二節(jié)LymphoidTissuesgans一、PrimaryLymphoidgans二、Secondary(peripheral)LymphoidTissuesg

7、ans三、LymphocyteTrafficRecirculation第三節(jié)PathologicalImmunityImmuneDiseases一、Knowimmunityisadoubleedgedswd二、ImmunemechanismsmaycausediseasesuchasHypersensitivityautoimmunediseaseetc.第四節(jié)BriefHistyProspectofImmunology一、Knowth

8、atthedevelopmentofimmunologyhasexperiencedthreestages.二、二、GraspthemaindiscoveriesofScientificImmunology三、GraspthemaindiscoveriesofModernImmunology思考題：1、Comparethedifferencebetweeninnateadaptiveimmunity？（五號宋體）第四節(jié)Biologica

9、lpropertiesfunctionsofimmunoglobulinclasses一、Graspthepropertiesofhumanimmunoglobulins.二、KnowthepropertiesofhumanIgGsubclasses.第五節(jié)AntibodytechnologyKnowthegeneralprocessoftheproductionofthemonoclonalantibody.思考題：1、Whatist

10、hemolecularstructureofimmunoglobulin2、Comparethedifferentenzymaticdigestionproductsofimmunoglobulins3、Whataretheconceptsofisotypesallotypesidiotypesofimmunoglobulins4、Whatarethemainbiologicalactivitiesofimmunoglobulins5、

11、Comparethedifferentbiologicalpropertiesfunctionsofimmunoglobulinclasses第五章TheComplementSystem課時：1周，共2課時教學內容第一節(jié)Introduction一、Knowthecomponentofcomplementsystem二、Knowthenomenclatureofcomplementsystem第二節(jié)Pathwaysofcomplement

12、activation一、Graspthetheclassicalpathwayofcomplementactivation二、Graspthelectinpathwayofcomplementactivation三、Comprehendthealternativepathwayofcomplementactivation四、Grasptheterminalsequencethemembraneattackcomplex第三節(jié)Regula

13、tionofcomplementsystemactivation一、Knowtheselfregulationcontrolofcomplementsystem二、Knowthefluidphaseregulationofcomplementsystem三、Knowthesolidphaseregulationofcomplementsystem第四節(jié)Biologicalconsequencesofcomplementactivatio

14、n一、Graspthebestknowncelllysisfunctionofthecomplementsystem.二、Graspopsonizationphagocytosisfunctionofcomplementsystem.三、Graspviralneutralizationfunctionofcomplementsystem.四、Graspinflammationfunctionofcomplementsystem.五、Co

15、mprehendregulationofcellsfunctionofcomplementsystem.六、Comprehendclearanceofimmunecomplexfunctionofcomplementsystem.思考題：1、Describethecomponentofcomplementsystem2、Whatistheclassicalpathwayofcomplementactivation3、Whatisthel

16、ectinpathwayofcomplementactivation4、Whatisthealternativepathwayofcomplementactivation5、Describetheregulationofcomplementsystemactivation6、Whatarethebiologicalconsequencesofcomplementactivation第六章Cytokines&第八章Leukocytedif