路易斯酸催化合成吡唑衍生物方法的研究.pdf

1、蘭州大學(xué)碩士學(xué)位論文路易斯酸催化合成吡唑衍生物方法的研究姓名：何勝申請(qǐng)學(xué)位級(jí)別：碩士專業(yè)：化學(xué)有機(jī)化學(xué)指導(dǎo)教師：梁永民20090501茂鍵文鼉2009唇頁士事業(yè)洽丈何勝abstractThisthesisaimsatthestudiesonthenewmethodforsynthesisofpyrazoleswithdiazoacetatecompoundstoterminalalkynesbyLewisacidcatalyzed，wh

2、ichisdividedtwopartsasfollows：PartI：TheresearchprogressofdiazocompoundsinorganicsynthesisInthispartwemainlyintroducledtheCOl／llnonreactiontypesofdiazocompoundsanditsapplicationinorganicsynthesisThecontentincluded：1，XH(su

3、ch鶴C—H，O—H，N—H)insertionreaction；2，cycloadditionreaction；3，13dipolarcycloadditionreactions；4，ylidereactionandSOonAtthesametimetherelateresearchresultsmadeinrecentyearsWaSsummarizedindetailsPartII：Studiesonthesynthesisofp

4、yrazoleswitlldiazoacetatescompoundstoterminalalkynespromotedbyLewisacidWedescribedahighlyeffectivemethodforthesynthesisofpyrazolederivativesUsingZn(II)ascatalystwesuccessfullyrealizedthe【32】eycloaddifionreactionoftermina

5、lalkynestodiazoacetatescompoundsThismethodshowsadvantagesintermsofeasilyavailablestartingmaterials，mildreactionconditionsandsimplicityofoperationInadditionthescopeofthesubstrateswereexamined，andapossiblereactionmechanism