鼻咽癌精確放療后遠處轉(zhuǎn)移分析及分子機制研究.pdf

1、分類號R739.6UDC610密級公開鼻咽癌精確放療后遠處轉(zhuǎn)移分析及分子機制研究鼻咽癌精確放療后遠處轉(zhuǎn)移分析及分子機制研究王建華培養(yǎng)類別非全日制學位類型學術學位一級學科(專業(yè)類)臨床醫(yī)學二級學科(專業(yè))腫瘤學研究方向腫瘤放射治療指導教師石梅教授培養(yǎng)單位西京醫(yī)院放療科二O一五年五月第四軍醫(yī)大學碩士學位論文目錄縮略語表縮略語表..........................................................

2、................................................................................................1中文摘要中文摘要...................................................................................................................

3、.......................................3ABSTRACT....................................................................................................................................................6前言.....................

4、.....................................................................................................................................9文獻回顧文獻回顧..............................................................................

5、..........................................................................11正文..............................................................................................................................................

6、..........16第一部分臨床研究.................................................................................................................................161材料..................................................................

7、..................................................................................161.1研究對象與臨床資料............................................................................................................................

8、.......162方法....................................................................................................................................................182.1放療方法...................................................

9、...................................................................................................182.2化療..................................................................................................................

10、............................................182.3隨訪..............................................................................................................................................................192.4統(tǒng)計學處理.

11、.................................................................................................................................................193結果......................................................................

12、..............................................................................193.1生存結果.....................................................................................................................................

13、..................193.2單因素分析結果...........................................................................................................................................203.3多因素分析結果.......................................

14、....................................................................................................223.4失敗模式...............................................................................................................

15、........................................223.5遠處轉(zhuǎn)移分析...............................................................................................................................................233.6不良反應.................

16、......................................................................................................................................244討論.................................................................................

17、...................................................................254.1鼻咽癌精確放療后生存及失敗模式............................................................................................................254.2預后因素................

18、.......................................................................................................................................264.3遠處轉(zhuǎn)移是影響生存的主要原因..................................................................

19、..............................................27小結........................................................................................................................................................29第二部分實驗研究........

20、.........................................................................................................................301材料..............................................................................................

21、......................................................301.1儀器和設備...................................................................................................................................................301.2試劑..

22、.............................................................................................................................................................301.3細胞系.......................................................

23、...................................................................................................312方法....................................................................................................................

24、.................................312.1組織標本收集...............................................................................................................................................312.2組織脫水........................