EEG偶極子在癲癇定位診斷中的應用.pdf

1、9碉158jr炎一：!墮衛(wèi)jj167級：冀——生一UDo^m——學％Q坐j東南碩女學大學位論文EEG偶極子在癲癇定位診斷中的應用研究牛舛名塑墮重導師姓名揚丟墮麴撞肯㈠綴Z0匡塋亟一J、W：l。監(jiān)幸i班、處型蘭f麴堡多t登塋!論文提交㈠圳!避j笙6最!!：旦一》文答辯[。刪!塑墨生鰻雖!!呂彳’位授J：單位—童一直杰蘭學位授弘r1期!魚旦!笙旦一旦答辯蛋員會I—i要房童一，—評閑人重墮一HG偶極了訂搗痛定位診斷中的應用Studyofthe

2、dipolesourcelocalizationforpre—operatiVelocalizationoftheepileptogenicdischargesinpaticntswithiⅡtractableepilepsyGraduate：guoxiaoyuanSuperVisor：yangtianmingAbstractobjectivc：Inorder10evalualetheefkctivenessofpresurgicald

3、ipoleanalysisofintenctalandseizu陀onsetphasespikesasanoninvasivetechniqucforthedete丌T1inationofepilcptogcnjcarea，wecomparedtheresuhsofthismethodwiththoseofelectrocorticography(ECoG)localizationandMR】Methods：25consecutivep

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5、dInterictala11dseizureonsetphasespikeswe陀analysisedbyBESAsoftware，whichprovidedmany“ndsofanalysjsmethods，suchasSequen“aldipolentting、initial6ttingofthespikepeak、regionalsource(4ofthem10sttheepilepticseizures’sEEGintheobs

6、crvation)Difkrentmethodsofdipolesourcelocalizationwerecomparedtoexploretherelationshjpoftheonsetregionandseizurere西onA11sampleswereexaminedinhist0109yandMRIresultswereconsjderedtojnvestigatethefactorsjn門uencingprognosisR

7、esuIts：Thed引krenceindip01e10ctionsbetweentheindiVidualandgrand—aVerageddatasetswasnotstatisticallysignincant11hemethodofdipolesourcelocalizationwasbetterthanroutineEEGjnspace—timediscriminationTheresultsusingsinglespikeo

8、raVeragedspikeanalysismethodshadnoobViouslyd訓了色renceHoweVer，averagedspikeanalysiswasthemoreef詫ctiVemethodstoobtainthebackgroundrh”hmic1naddition，MRlresultsindicatedthecorrelationofhippocampussclerosjsandepileptogenic1esi

9、n，whichcon^rmedbypostoperationpath0109yConclusion：TheanalysistoEEGshouldbeonthebasisofneuroanatomyandelectrophysjologyknowledgeDipoIesourcelocalizationmethodwasbetterthanroutineEEGinspace—timediscrimination1owever，becaus