不同時相電針對血管性癡呆大鼠海馬IL-1β、TNF-α含量及其超微結(jié)構(gòu)的影響.pdf

1、貴陽中醫(yī)學(xué)院碩士學(xué)位論文不同時相電針對血管性癡呆大鼠海馬IL1β、TNFα含量及其超微結(jié)構(gòu)的影響姓名：忽浩杰申請學(xué)位級別：碩士專業(yè)：針灸推拿學(xué)指導(dǎo)教師：朱廣旗20090601貴lf幾中醫(yī)學(xué)院碩I：學(xué)位論文ABSTRACTObjective：Toobservetherelationshipbetweenchangesofinterleukin一113(IL一113)andtumornecrosisfactor—Q(TNF一0【)conte

2、ntinginthehippocampusandlearning—memoryabilityinvasculardementia(VD)ratsbyelectroacupuncture(EA)，theprojectaimstoexplorethepossiblemechanismofacupuncturetreatmentforVDandgainsomeevidencefortheclinicaltreatmentMethods：8ra

3、tschosenrandomlyfrom80properoneswereconsistedofmodelgroupVDmodelwasestablishedbyusingPulsinelli’S4vesselocclusion(4VO)techniqueonSDratsEAWasappliedto“Baihui”(GV20)and“Dazhui”(GV14)，“Shenshu”(BL21)and“Geshu”(BL17)inbothsi

4、desfor20min，twiceadayandfor5daysAbilitiesoftheratslearning—memoryistestedbyMorriswatermazeContentsofIL—l13andTNFQinhippocampustissuetakenfromthekilledratsheadismeasuredbyusingenzymelinked—immunoassay(ELISA)techniqueSuper

5、con—structureofhippocampustissueinrats’brainofeverygroupisobservedbyTEMResults：OPlacenavigationtestandspaceprobetestcomparedwithcontrolgroupshowedthat，themeanescapelatenciesandthetimesofcrossingtheoriginalplatformquadran

6、tinmodelgroupweresignificantlylongerandmore(Po01)②AfterapplyingEAonmodelrats，thecomparisonofratlearningmemoryability：Differencebetween1phasemodelEAgroupand1phasemodelcomparativegroup，differencebetween2phasemodelEAgroupan

7、d2phasemodelcomparativegroup，aresignificant(Pl001、P2005)。Differencebetween3phasemodelEAgroupand3phasemodelcomparativegroupisnotsignificant1phaseEAgroupwassignificantlysuperiorthan23phaseEAgroup(P001)2phaseEAgroupwassigni

8、ficantlybetterthanthe3phaseEAgroup(PO01)ThecomparisonofcontentsofIL113andTNF一0【inhippocampustissue：Differencebetween1phasemodelEAgroupand1phasemodelcomparativegroup，anddifferencebetween2phasemodelEAgroupand2phasemodelcom