應(yīng)用組織芯片技術(shù)研究喉癌中人光蛋白聚糖（lumican）的表達(dá)及意義.pdf

1、佳木斯大學(xué)碩士學(xué)位論文應(yīng)用組織芯片技術(shù)研究喉癌中人光蛋白聚糖（lumican）的表達(dá)及意義姓名：溫延輝申請(qǐng)學(xué)位級(jí)別：碩士專(zhuān)業(yè)：耳鼻咽喉科學(xué)指導(dǎo)教師：姚雅芬張愛(ài)華200806052佳本斯大學(xué)碩士學(xué)位論文AbstractObjectiveExploretherelationshipofLumicanexpressionwithtumorigenesisandprogressionofthelaryngealcarcinoma，andwith

2、clinicalsymptomsandpathologicalmechaniSillofthiscancerMethods：Thetissuechipsoflaryngealcarcinomatissuesandthecorrespondingnormalepitheliummucosaetissueswereconstructed：andthenthestatisticalanalysiSofthetestedLumincanexpr

3、essionapplyingtheimmunohistochemicalmeasureswerecarriedoutResultsTheLumicanexpressionratiointheiaryngealcarcinomatissues(742％)isobviouslyhigherthantheexpressionratio(274％)inthosenormaltissuesnearthecolorectalcancertissue

4、s，(PO05)ConcIusions：Lumicandidn’texpressorlowexpressinnormallaryngealcel1butexpressedorhighexpressedincancerouscell，itsuggeststhatLumicanplaysaroleatthegenerationoflaryngealcancer：TheexpressionofLumicanhasnocorrelationwi

5、thpatient’Sage，sex，attackinglocation，lymphnodemetastasiSanddifferentiationofpatientsItsuggeststhatitseffectonlaryngealcanceriSnotaffectedbypatient’Sage，sex，attackinglocation，lymphnodemetastasisanddifferentiationofpatient