KAI1-CD82和Ki-67在上皮性卵巢癌中的表達.pdf

1、分類號單位代碼：10343學導：20022033⑨濕州嚼訾院在職申請碩士學位論文論文題目：叢』!蟹墅墼塑墜2壟土應性鯉盥瘟主啦趨盤研究生姓名：土紅學科專業(yè)：婦產(chǎn)科指導教師：楊祖菁二OO六年九月溫州醫(yī)學甓碗士學蹙論文AbstractExpressionofKAll／CD82andKi67inEpithelialOvarianCallCerCellsObjec伽es：ToinvestigatetheexpressionofKA／1／CD92

2、andKi67inepithelialovariancancercellsTheresultstoge也erwiththedime81dataWereusedtotestthevalidityandreliabilityofthismethodMethods：ImmunohistochemicalEnVisionmethodwasappliedtOdeterminetheexpressionlevelsOfKAll／CD92andKi6

3、7inepithelialcallccrtissuespecimensResults：TheabsanceOl“l(fā)owexpressionofKAIlJCD92WaSobserved面22％patientswithbenignovarianneoplasmandin92％patientswithmalignantepithelialovariancancerrespectivelyThesetwogroupsshowedsignific

4、antdifference∞o0t)InadditionamarkeddifforeneewasalsoobservedbetweenGfandG2G3Rllilorswi也correspondingloss01“l(fā)owexpressionofKAII／CD82at67％and96％，respectivelyCo005)HoweversuchdifferencedidnotexistintermsofthesizeofRimot)the

5、quantityofascites，thetypeOfRlmorandthestageofFIGOHi曲expressionratesofKi67inbenignovarianneoplasm(55％)andmalignantovarianepithelialcancer(66％)showedsignificantdifference(p(o01)，whichⅧobservedbetweenG1andG2G3tIlmD≈aswell(p

6、O01)InadditionthehighexpressionlevelofKi67Was920／0whenasciteswasnotless也an500raland52％whenasciteswaslessthan500nilghowingsignificantdifference睡O0s)HOWeVersuchdiffet目acediditotexistintermsofthesizeoftumor’thetypeoftumoran

7、dthestageofFIGO。Theloss講lowexpressionrateofKAIl，cD82inthetumorun—recumuggrouprecurringgroup，anddeathgroupwas78％，100％，and100％，respeetivdyInconWastthehi曲expressionlevelofKi67inthecorrespondinggroupWaS500／0，1000／0，and67％res