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1、一、投稿信1.DearDr.DefendiML:Iamsendingamanu.entitled“”by–whichIshouldliketosubmitfpossiblepublicationinthejournalof.Yourssincerely2.DearDr.A:Enclosedisamanu.entitled“”bysbwhichwearesubmittingfpublicationinthejournalof.Wehave

2、chosenthisjournalbecauseitdealswith.Webelievethatsthwouldbeofinteresttothejournal’sreaders.3.DearDr.A:Pleasefindenclosedfyourreviewaniginalresearcharticle“”bysb.Allauthshavereadapprovethisversionofthearticleduecarehasbee

3、ntakentoensuretheintegrityofthewk.Nopartofthispaperhaspublishedsubmittedelsewhere.NoconflictofinterestexitsinthesubmissionofthismanuwehaveattachedtothisletterthesignedlettergrantinguspermissiontouseFigure1fromanothersour

4、ce.Weappreciateyourconsiderationofourmanuwelookfwardtoreceivingcommentsfromthereviewers.二、詢問(wèn)有無(wú)收到稿件DearEditsWedispatchedourmanu.toyourjournalon3August2006buthavenotasyetreceiveacknowledgementoftheirsafearrival.Wefearthatm

5、ayhavebeenlostshouldbegratefulifyouwouldletusknowwhethernotyouhavereceivedthem.Ifnotwewillsendourmanu.again.Thankyouinadvancefyourhelp.三、詢問(wèn)論文審查回音DearEdits,Itismethan12weekssinceIsubmittedourmanu.(No:)fpossiblepublication

6、inyourjournal.Ihavenotyetreceivedareplyamwonderingwhetheryouhavereachedadecision.Ishouldappreciatedyourlettingmeknowwhatyouhavedecidedassoonaspossible.四、關(guān)于論文的總體審查意見(jiàn)1.Thisisacarefullydonestudythefindingsareofconsiderablei

7、nterest.Afewminrevisionarelistbelow.2.Thisisawellwrittenpapercontaininginterestingresultswhichmeritpublication.Fthebenefitofthereaderhoweveranumberofpointsneedclarifyingcertainstatementsrequirefurtherjustification.Therea

8、regivenbelow.3.AlthoughtheseobservationareinterestingtheyareratherlimiteddonotadvanceourknowledgeofthesubjectsufficientlytowarrantpublicationinPNAS.Wesuggestthat11.Ifeelthatthereviewer’scommentsconcerningFigures12resultf

9、romamisinterpretationofthedata.12.Wewouldhaveincludeanonproteininhibitinoursystemasacontrolifonehadbeenavailable.13.WeprefertoretaintheuseofTable4freasonsthatitshouldbeclearfromthenewparagraphedattheendoftheResultssectio

10、n.14.Althoughreviewerdoesnotconsideritisimptanttomeasurethetemperatureofthecellsweconsideritessential.15.Therunningtitlehasbeenchangedto“”.16.TheMaterialsMethodssectionnowincludesdetailsfmeasuringuptakeofisotopeassayingh

11、exokinase.17.TheconcentrationofHATmedia(page12paragraph2)wasincrectlystatedintheiginalmanu.Thishasbeenrectified.Theauthsaregratefultotherefereesfpointingouttheirerr.18.Assuggestedbybothrefereesadiscussionofthepossibility

12、oflaseractiononchromosomehasbeenincluded(page16paragraph2).19.Weincludedanewsetofphotographswithbetterdefinitionthanthoseiginallysubmittedtowhichascalehasbeenadded.20.FollowingthesuggestionoftherefereeswehaveredrawFigure

13、34.21.TwofurtherpaperspublishedsinceouriginalsubmissionhavebeenaddedtothetextReferencesection.Theseare:22.Weshouldliketothanktherefereesftheirhelpfulcommentshopethatwehavenowproducedamebalancebetteraccountofourwk.Wetrust

14、thattherevisedmanu.isacceptablefpublication.23.Igreatlyappreciatebothyourhelpthatoftherefereesconcerningimprovementtothispaper.Ihopethattherevisedmanu.isnowsuitablefpublication.24.Ishouldliketoexpressmyappreciationtoyout

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