微米級(jí)功能高分子微球的一步合成及與生物大分子相互作用的研究.pdf

1、華中師范大學(xué)碩士學(xué)位論文微米級(jí)功能高分子微球的一步合成及與生物大分子相互作用的研究姓名：李武客申請(qǐng)學(xué)位級(jí)別：碩士專業(yè)：有機(jī)化學(xué)指導(dǎo)教師：李松軍20061101⑧顧士學(xué)住論文MASTER’STHESISAbstractMicron—sizedpolymermicrospheres，duetoitsadvantagesofhighspecific—surfacearea，monodispersityaswellasfacileprepara

2、tionandfunctionalization，hivebeenoneoffocusesintherecentyearsTheapplication‘ofpolymermicrospherescannotonlysubstitute，inpart，naturalbiomaterialbutalsoexpanditsapplicablerangelargelytherebypresentingawideprospectiveforvar

3、iousfieldssuchasbiomedicine，materials，information，food，chemicalengineerandbiologicalfieldsetcInthepresentdissertation，aseriesoftentativeworksinvolvingthesynthesisofmicron—sizedpolymermicrospheresandtheirfunctionalization

4、，theinteractionbetweenthesynthesizedsuppoftandbiomacromoleculesaswellasthemodificationofclassictheorieswerepresentedForthesynthesis，one—stepwisedispersionpolymerizationwasemployedTwomicron—sizedmonodispersitypolymerswith

5、bioactivitysurfaciallywaspreparedbasedontheparticipatedmonomerwhichcontainsactivealdehydeandsulfonicgroupsWithbovineseillmalbuminastargetmoleculeandthesynthesizedmicrospheresassupport，theinteractionmechanismofsupport—bio

6、macromoleculewasstudiedRelatedinformationindicatedthattheinteractionmechanismismuchmorecomplicatedincomparisont0classictheoreticalsystemsincludingidealizedLangmuirmodelandpracticalFreundlichorTemldntheoriesTointerpretthe

7、practicalprocessbettertheclassictheoriesweredevelopedandwhichultimatelypresentsamorelogicalresultFurtherinformationalsorevealsthattheadsorptionandimmobilizationofbiomacromoleculesuchasenzymehavesignificanteffectontheacti

8、vitystabilityandconformationereTheimmobilizationimprovesnotonlytheperformanceofthermo—resistanceandthedepositingstabilitybutalsoincreasesthecapabilityofanti—acidsorbases，whichthuspavethewayforlongl[imeandconsecutiveusesK