金屬參與的有機(jī)硒合成新方法及組裝新型分子梭關(guān)鍵砌塊的合成.pdf

1、湖南大學(xué)碩士學(xué)位論文金屬參與的有機(jī)硒合成新方法及組裝新型分子梭關(guān)鍵砌塊的合成姓名：黃榮新申請(qǐng)學(xué)位級(jí)別：碩士專業(yè)：有機(jī)化學(xué)指導(dǎo)教師：許新華20030621AbstractOrganicselenideshaveattractedmoreandmoreattentionsofchemistspharmacologistsandbiologistsfortheirimportantroleintheorganicsynthetictransf

2、ormationandtheirlatentbiologicalactivitiesItisahottopicinthefieldoftheirnewsyntheticmethodsandtheresearchoftheirbioactivitiesButtherearesomedisadvantagesinthesyntheticmethodsoforganicselenidessuchasneedingstemconditionsf

3、orreactionusingpoisonousmaterialsandprocessingcomplicatedmulti—stepprocessWeputforwardanovelmethodforsynthesizingtheallylsetenidesbycheaperandinnoxiouszincreagentsSuchmethodcallaffordhighyieldsandhassimpleoperationsJ~1ky

4、nylselenidesareaspeciesofimportantintermediatesinorganicsynthetictransformations，currentlytheirsyntheticmethodsneednowaterandnooxygenoperationsandtheiryieldsaremuchlowerConsideringthehighestbasicityofcesiumhydroxideWepla

5、ntouseterminalalkynesreactwithdiaryldiselenidestOaffordalkyIllselenidesThismethodhastheadvantagesofsimpleoperationandwithoutWOrryingaboutthepresenceofwaterandoxygenMolecularshuttleisthebasiccompoundforconstructingmolecul

6、armachineTheresearchinthisfieldisinafiontfieldofscienceWefirstlyputforwardthetorpidmolecularshutileandtheinnersaltmolecularshuttleduotothestrueturalcharacterofproteinandlecithin，andwehavedesignedtwospeciesofthesemolecula

7、rshuttlesTheblocksforconstructingtotheseshu仕lesweresynthesizedTheinfectionsofsyntheticmethodsandconditionsOilthemulti—stepprocessarediscussedIntermediatesandobjectivemolecularsynthesizedarecharacterizedby1HNMR、13CNMRand3