氯化鈷-席夫堿均相雙羰化體系的催化性能研究.pdf

1、華中科技大學(xué)碩士學(xué)位論文氯化鈷席夫堿均相雙羰化體系的催化性能研究姓名：李琳申請學(xué)位級別：碩士專業(yè)：有機(jī)化學(xué)指導(dǎo)教師：李光興2002.5.11華中科技大學(xué)碩士學(xué)位論文AbstractDoublecarbonylationisallimportantfieldofC1chemistryManycatalystsusedinthedoublecarbonylationofbenzylchloridetophenylpyruvicacid(PP

2、A)havesomeshortagessuchasdifficulttosynthesize，lessstabilityandveryexpensiveAimingatthese，anovelcatalystsystemisfoundtOhavehi曲stabilityandhighselectivityforthedoublecarbonylationofbenzylchloridetoPPAindioxane／H20systemTh

3、econditionsandcatalysisactivityofCoCl棚KPycaarestudiedinthispaperTheeffectsofreactiontemperature，COpressure，theconcentrationofcatalyst，thesolventandthestirringhavebeentestedsystematicallyInthecaseofCOCl2O035mol／1KPycaO13m

4、ol／l，themolratioofCa(OH)2]PhCH2C120，theV(dioxane)／V(I120)5：1，theconversionofbenzylchlorideis907％，andtheyieldofPPAis87％晰tIlselectivity967％whenthereactioniscarriedoutfor10hat353Kand28MPaAtthesanletimethemachanismofcatalyst

5、synthesizedintheautoclaveanddoublecarbonylationhasbeendiscussed。7西edifferenceofactiveintermediatesinCoCl2／KPycasystemandcatalystC02(C0)8inthedoublecarbonylationiscomparedandthereactionmacha／lismthatPPAissynthesizedisdedu

6、cedItisfoundthatthecontentofPPAinmixturecouldbeanalyzedquicklyandconvenientlybycolourimetryIntheaqueoussolutionofacetateandDMSOPPACancoordinatewithFe3toformacomplex，whichhasabsorbenceat640nm，whileB—benzylphenylpyruvicaci

7、d(BPPA)doesnothavethispropertyOnbasisofthisprinciplethecontentofPPAcallbeanalyzedquantativelyAtthesametimethecharacterizationsofPPAandBPPAbyU、‘玨IMSand1HNMRhavebeencarriedoutThesespectraalediscussedindetailaccordingtothed

8、ifferenceoftheirslructuresTherecoveryofCoClffKPycacatalystsysteminthedoublecarbonylationisalsostudiedThecatalystCanberecycledforthreetimesandtheyieldofPPAdoesnotdecreasedramaticallyButaccordingtothephysicallossofseveralt