肝轉移瘤經(jīng)肝動脈介入治療療效評價及影響因素分析.pdf

1、中國協(xié)和醫(yī)科大學碩士學位論文肝轉移瘤經(jīng)肝動脈介入治療療效評價及影響因素分析姓名：閆東申請學位級別：碩士專業(yè)：影像醫(yī)學與核醫(yī)學指導教師：李槐20040501中國協(xié)和醫(yī)科大學中國醫(yī)學科學院碩士研究生畢業(yè)論文Evaluationofefficacyandprognosticfactorsinthepatientsoflivermetastasestreatedwithinterventionaltherapybyhepaticartery[A

2、bstract]ObjectiveToevaluatetheefficacyandvalueintheDatientsof1ivermetastasestreatedwithregionaltherapyofhepattcarteryinCox’SregressionmultivariateanalysesMethodsOf470patientSwithlivermetastasesweretreatedbyregionaltherap

3、yofhepaticarteryjn1231timesAntitumoragentswereselectedaccordingtothepathologicresultsoforigintumor，addedembolizationwith1ipiodolultra—fluid(LUF)or／andgelatinspongetothepatientsofhypervascularCoxregressionwasusedinproport

4、ionalhazardanalysisResponserateswereassessedbyCTscanResultsThemediansurvivalperiod(MS)of470patientswas135monthsAnoverallresponserate(CRPR)was504％The05一，10一，2O，30一，5Oyearsurvivalratewas86。4％、668％、356％、169％、73％respectively

5、TherewasnoseveresideeffectandeomplicationCoxregressionmultivariableanalysesshowedthattheMSofthepatientswithhypervascular、resectedoforigintumor、singlelesion、withouttumorthrombusinportalvein、adjuvantchemotherapyafterregion

6、altherapyofhepaticarteryandoriginatedfrombreastcancerwerelongerthantheothers(尸O01)，Thesurvivalperiodwas10ngerinthepatientsinvolvedofalobeof1iverandwithoutmetastasestotheothersites(PO05)ConclusionTheregionaltherapyofhepat

7、icarteryiSabetterwayforlivermetastasesThoseofabovementionedweremaininfluencefactorsinthepatientswith1ivermetastasestreatedbyregionaltherapyofhepatiCartery[Keywords]Livermetastasis：Regionaltherapy：Hepaticartery：Treatmente