國產(chǎn)與進口全氟正辛烷對兔眼影響的差異.pdf

1、復旦大學碩士學位論文國產(chǎn)與進口全氟正辛烷對兔眼影響的差異姓名：王玲申請學位級別：碩士專業(yè)：眼科學指導教師：陳欽元2001.5.1lnvestigationofDifferentEffectsonRabbitEyesofHomemadeandImportedPerfluoro—n—OctaneFluidsWangLingSupervisor：ChenQinyuan(Abstract)Background：Highlypurifiedper

2、fluoronoctane(PFnO)fluidiswildlyusedinvitreoretinalsurgerynotonlyforitsgoodstabilityandvisualizationduringoperation，butalsoforitslowretentionaftersurgerySomeinstimtionsinShanghaiarenowtryingtosynthetizePFnObythemselvesto

3、substitutetheimportedoneinophthalmicsurgeryPurpose：ToinvestigatethedifferenteffectsOnrabbReyesof似osamplesofhomemadeperfluoron—octanefluidsandimportedone(Perfluoron，Alcon)，evaluatetheviabilityofhomemadePFnOusedasavi仃eouss

4、ubstituteinvitreoretinalsurgeryandexploretheopportunemomentofdrawingouttheretainedPFnOintheanteriorchamberMethods：PneumovitrectomyWaSperformedon34Newzealandwhiterabbits(68eyes)oneweekbeforetheeyeswereinjectedwithdifferen

5、tsamplesofhomemadePFnOfluidsandPerfluoronintheanteriorchamberandthevigeouscavityfor3hours，6hours，24hours，72hours，1week，2weeks，1month，andupto2monthsAlleyeshadclinicalexaminationandelectroretinographicstudybythesameresearc