丁苯酞對大鼠腦缺血再灌注損傷后細胞色素-C表達影響的研究及意義.pdf

1、山西醫(yī)科大學碩士學位論文丁苯酞對大鼠腦缺血再灌注損傷后細胞色素C表達影響的研究及意義姓名：王建華申請學位級別：碩士專業(yè)：神經(jīng)病學指導教師：劉瑞珍20100310山西醫(yī)科大學碩十學位論文Theexpressionofc”ochrome—canditssignilEicanceinthetreatmentofBu鑼lphthalideoncerebralischemia—reper如sion螄u巧AbstractobjectiVe：cere

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7、tllalidepreVention鏟oup；withacom豳∞uSgavageonceadayone、Ⅳeekbe南retheoperation鋤d岫ectButylpht量lalidedilutionby硫raperitonealmer1hischemiaiIlButylphtllalidepreVentiontreatnlemgroup；iIlsllamoperalion掣oup鋤dmodel伊oup，硒ecttbesaInes

8、alineafter1hischemiaBraillpathologywithHEsta血iIlg，obsen，ethecllal喀eofcytochroIneci11bramtissuewithimmuneStailliIlg，detectapoptoticcellswithTUNELResults：1Usingmodi托dsuturemethodcallproduceMACO瓜nlodelsuccessmlly，focalische

9、micbrailltissuecanbeobseⅣedobViously2Therearedi彘rentdegreesofedemaandcaVity向m蚍ionscatteredh1theischemicbrailltissueofcerebralischemiarepermsionmodel伊oup，thenulllberofapoptoticcellsi11creasedsigm&antlyTherearevar)，ingdegr

10、eesofilnproVemem證preventionandtreatment伊oup3Comparewithsh甜n—operated鏟oup，cytochroIne—cexpressionaIldthe肌mberof印optoticcellsiIlcreaSedsignificantlyiIlthecerebralischemiareper如sionmodelgroup；iIlthepreVentiongroup，協(xié)；atmentg