膜聯(lián)蛋白A1在小細(xì)胞肺癌骨轉(zhuǎn)移中的作用及分子機(jī)制的研究.pdf

1、 博士學(xué)位論文膜聯(lián)蛋白 膜聯(lián)蛋白 A1 在小細(xì)胞肺癌骨轉(zhuǎn)移中的作用 及分子機(jī)制的研究 在小細(xì)胞肺癌骨轉(zhuǎn)移中的作用 及分子機(jī)制的研究 張 峰 培 養(yǎng) 類 別 全日制 學(xué) 位 類 型 學(xué)術(shù)學(xué)位 一級(jí)學(xué)科(專業(yè)類) 臨床醫(yī)學(xué) 二 級(jí) 學(xué) 科 ( 專 業(yè) ) 腫瘤學(xué) 研 究 方 向 肺癌骨轉(zhuǎn)移相關(guān)機(jī)制 指 導(dǎo) 教 師 張賀龍 教授（主任醫(yī)師） 培 養(yǎng) 單 位 唐都醫(yī)院腫瘤科 二 O 一三年五月 分 類 號(hào) U D C 密

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22、·························27 實(shí)驗(yàn)一 膜聯(lián)蛋白 A1 在不同骨轉(zhuǎn)移潛能小細(xì)胞肺癌細(xì)胞株中的表達(dá) ·····

23、83;············27 1 材料........................................................................................................................ 28 2 方法..........

24、.............................................................................................................. 30 3 結(jié)果......................................................................................................

25、.................. 35 4 討論........................................................................................................................ 36 實(shí)驗(yàn)二 膜聯(lián)蛋白 A1 在小細(xì)胞肺癌細(xì)胞中的生物學(xué)作用·······

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27、............................................................................................. 39 2 方法.......................................................................................................................

28、. 42 3 結(jié)果........................................................................................................................ 53 4 討論...................................................................................

29、..................................... 65 實(shí)驗(yàn)三 膜聯(lián)蛋白 A1 促進(jìn)小細(xì)胞肺癌骨轉(zhuǎn)移機(jī)制的初步探討 ························

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31、................................................................... 69 3 結(jié)果........................................................................................................................ 70 4 討論.................

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