尼古丁調控細胞自噬參與人牙周膜細胞炎性損傷的作用研究.pdf

1、尼古丁調控細胞自噬參與尼古丁調控細胞自噬參與人牙周牙周膜細胞膜細胞炎性炎性損傷的作用研究損傷的作用研究杜樣學號2162014360培養(yǎng)類別全日制學位類型學術學位一級學科(專業(yè)類)口腔醫(yī)學二級學科(專業(yè))口腔臨床醫(yī)學（兒牙）研究方向吸煙相關性牙周炎機制研究指導教師王小競教授（主任醫(yī)師）培養(yǎng)單位口腔醫(yī)院兒童口腔科二O一七年五月UDC616.31密級公開第四軍醫(yī)大學碩士學位論文目目錄錄縮略語表.........................

2、.....................................................................................................1中文摘要..................................................................................................................

3、............3英文摘要..............................................................................................................................6前言..........................................................................

4、..................................................10文獻回顧............................................................................................................................12正文....................................

5、........................................................................................28實驗一hPDLCs的培養(yǎng)與鑒定.................................................................................281材料.............................

6、............................................................................................282方法.........................................................................................................................29

7、3結果.........................................................................................................................314討論...........................................................................................

8、..............................33實驗二尼古丁對hPDLCs自噬水平的影響...........................................................351材料........................................................................................................

9、.................352方法.........................................................................................................................363結果........................................................................

10、.................................................394討論.........................................................................................................................45實驗三尼古丁通過調控hPDLCs自噬水平的研究....................

11、...........................471材料.........................................................................................................................472方法..............................................................

12、...........................................................483結果.........................................................................................................................494討論..............................

13、...........................................................................................53實驗四尼古丁通過調控hPDLCs自噬水平調節(jié)炎性因子的表達.........................551材料....................................................................

14、.....................................................552方法.........................................................................................................................563結果....................................