有機(jī)雙過(guò)氧釩化合物的合成及其與幾種小分子相互作用研究.pdf

1、廈門(mén)大學(xué)碩士學(xué)位論文有機(jī)雙過(guò)氧釩化合物的合成及其與幾種小分子相互作用研究姓名：黃婷申請(qǐng)學(xué)位級(jí)別：碩士專(zhuān)業(yè)：物理化學(xué)指導(dǎo)教師：陳忠20060501SynthesesofOrganicDiperOxoVanadatesandInteractionswithSomeSmallMoleculesTingHuangABSTRACTInthepasttwodecades，theinteractionsbetweenperoxovanadatesan

2、dorganicligandshaveattractedgreatinterestinbothchemistryandbiologyInthiswork，multinuclearNMR(1H，BC，14Nand51v)，multidimensional(DOSY1H_lHcosYand”C)Hcosy)，andvariabletemperatureNMRwereutilizedtostudytheaboveinteractionsyst

3、emsThroughthecombinationofthesemethods，structuresofallspeciesininteractionsystemswereobtainedandabetterunderstandingoftheexperimentalphenomenawasachievedThesestudiesshedsomelightontheessenceofthevanadium—containedenzymes

4、uchaschloroperoxidaseThemainconclusionsaresummarizedasfollows：1MultinuclearNMRmultidimensionalandvariabletemperatureNMRtechniqueswereusedtostudytheinteractionsbetweendiperoxovanadatesandsmallorganicmoleculessuchassubstit

5、utephenanthrolineandoxazoleTheirstereochemicalstructuresinsolutionwerediscussedaccordingtotheNMRsignalsoftheorganicligandsAll1Hand13CpeakswerecompletelyassignedandthepredominantinteractionpattemofthesecomplexesWaspropose

6、d2NMRstudyontheinteractionsbetweendiperoxovanadatesandhistidinelikeligandsshowsthatGlyHisandGlyHisGlycoordinatestovanadate(V)byits￡—NwhichisthesameasHis496intheactivesiteofchloroperoxidasefromthefungusCurvularMinaequalis